Description

Benzyl trans-3-Hydroxycyclobutanecarboxylate CAS NO 128041-58-7 is a high-purity, synthetically valuable chiral building block featuring a cyclobutane core. This compound matters as a versatile intermediate for constructing complex molecular architectures in advanced pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as API synthesis and the creation of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides where the rigid cyclobutane structure can impart unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science: Potential monomer or cross-linking agent for synthesizing specialty polymers with tailored thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function or cellular pathways.
• Fragrance and Flavor Chemistry: Intermediate for the synthesis of complex aroma chemicals with specific stereochemical requirements.

Basic Information

Product Name	Benzyl trans-3-Hydroxycyclobutanecarboxylate
CAS No.	128041-58-7
Molecular Formula	C12H14O3
Molecular Weight	206.24 g/mol
Synonyms	trans-3-Hydroxycyclobutanecarboxylic Acid Benzyl Ester; Benzyl (1r,3r)-3-Hydroxycyclobutanecarboxylate; (1R,3R)-3-Hydroxycyclobutanecarboxylic Acid Benzyl Ester; Benzyl 3-Hydroxycyclobutanecarboxylate (trans-); Cyclobutanecarboxylic acid, 3-hydroxy-, benzyl ester, (1R,3R)-; Benzyl Oxycyclobutanecarboxylate
EINECS	Contact for details

Quality Control

Our Benzyl trans-3-Hydroxycyclobutanecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.