Description

7-Hydroxyethyl-1-Oxacephem is a key advanced pharmaceutical intermediate belonging to the oxacephem class of β-lactam compounds. This high-purity intermediate is critical for the synthesis of novel and potent antibiotics, offering a versatile scaffold for further chemical modification. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation antimicrobial agents to address growing antibiotic resistance.

Application

• Pharmaceutical Intermediate: Core building block for the synthesis of advanced oxacephem and cephalosporin antibiotic candidates.
• Antimicrobial Research: Used in medicinal chemistry programs to develop new antibacterial agents with improved spectra and potency.
• Process Chemistry: Serves as a critical starting material or intermediate in the scale-up and optimization of antibiotic manufacturing processes.
• Biochemical Studies: Employed in research to study structure-activity relationships (SAR) and the mechanism of action of β-lactam antibiotics.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API production.

Basic Information

Item	Detail
Product Name	7-Hydroxyethyl-1-Oxacephem
CAS No.	128022-92-4
Molecular Formula	C10H15NO5S
Molecular Weight	261.30 g/mol
Synonyms	(6R,7R)-7-[(R)-2-Hydroxyethylthioacetamido]-3-methyl-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; 7-(2-Hydroxyethylthioacetamido)-3-methyl-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; 7-HEO; 7-Hydroxyethyl Oxacephem Intermediate; 7-[(2-Hydroxyethylthio)acetamido]-3-methyl-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 7-Hydroxyethyl-1-Oxacephem is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.