Description

n-4-Boc-2-Piperazinecarboxylic Acid CAS NO 128019-59-0 is a high-purity, protected piperazine derivative widely used as a critical building block in organic synthesis. This compound is essential for the development of novel pharmaceuticals and bioactive molecules, offering a versatile scaffold for constructing complex chemical architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediates: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and kinase inhibitors.
• Peptidomimetics & Drug Discovery: Serves as a constrained scaffold for designing and synthesizing peptidomimetics and novel small molecule libraries.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for the piperazine nitrogen, enabling selective synthetic transformations.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and herbicides.
• Ligand & Catalyst Development: Acts as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A fundamental component for custom synthesis services catering to the needs of biotechnology and pharmaceutical clients.

Basic Information

Product Name	n-4-Boc-2-Piperazinecarboxylic Acid
CAS No.	128019-59-0
Molecular Formula	C10H18N2O4
Molecular Weight	230.26 g/mol
Synonyms	1-Boc-piperazine-2-carboxylic acid; 1-(tert-Butoxycarbonyl)piperazine-2-carboxylic acid; 2-Piperazinecarboxylic acid, 1-(1,1-dimethylethoxy)carbonyl]-; tert-Butyl 2-carboxypiperazine-1-carboxylate; 1-N-Boc-piperazine-2-carboxylic acid; 4-Boc-2-piperazinecarboxylic acid; Boc-Pip(2)-OH; 1-Boc-piperazine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our n-4-Boc-2-Piperazinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.