Description

(L)-n-Benzyloxycarbonyl-Proline-Tert Butylamide is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the precise construction of complex peptide structures and other bioactive molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents and specialized chemical intermediates.

Application

• Peptide Synthesis: A key protected proline derivative used as a chiral intermediate in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Research: Serves as a crucial building block in the research and development of new drug candidates, particularly peptidomimetics and protease inhibitors.
• Combinatorial Chemistry: Utilized in the generation of diverse chemical libraries for high-throughput screening in drug discovery programs.
• Bioconjugation: Acts as a linker or spacer molecule in the design of antibody-drug conjugates (ADCs) and other bioconjugates.
• Fine Chemical Intermediate: Employed in the custom synthesis of complex organic molecules requiring a protected proline moiety.
• Academic Research: Used in university and institutional laboratories for studies in organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	(L)-n-Benzyloxycarbonyl-Proline-Tert Butylamide
CAS No.	128018-17-7
Molecular Formula	C17H24N2O4
Molecular Weight	320.39 g/mol
Synonyms	Z-Pro-NHtBu; Nα-Cbz-L-Proline tert-Butylamide; (S)-1-(((Benzyloxy)carbonyl)pyrrolidine-2-carboxamide); N-Carbobenzoxy-L-proline tert-butylamide; Cbz-L-Pro-NH-tBu; Nα-Z-L-Proline tert-Butylamide; L-Proline, N-[(phenylmethoxy)carbonyl]-, 1,1-dimethylethyl ester; Benzyl (S)-2-(tert-butylcarbamoyl)pyrrolidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our (L)-n-Benzyloxycarbonyl-Proline-Tert Butylamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the stringent requirements of pharmaceutical research and fine chemical synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.