Description

(1S,2R)-n-Tosylephedrine is a high-purity chiral intermediate and building block of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry, which is critical for producing enantiomerically pure pharmaceutical compounds and fine chemicals. This product is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring specific stereochemical configurations for efficacy.
• Asymmetric Synthesis: Used as a building block or auxiliary in catalytic and stoichiometric asymmetric reactions to induce chirality in target molecules.
• Medicinal Chemistry Research: Employed in the discovery and development of new drug candidates, especially within central nervous system (CNS) and adrenergic receptor modulator research.
• Fine Chemical Production: Serves as a precursor for manufacturing complex, high-value specialty chemicals and performance materials.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in chromatographic analysis.

Basic Information

Product Name	(1S,2R)-n-Tosylephedrine
CAS No.	127641-25-2
Molecular Formula	C17H21NO3S
Molecular Weight	319.42 g/mol
Synonyms	(1S,2R)-(-)-N-(p-Toluenesulfonyl)ephedrine; (1S,2R)-N-Tosyl-(-)-ephedrine; (-)-N-Tosylephedrine; (1S,2R)-1-Phenyl-2-(methylamino)-1-propanol 4-methylbenzenesulfonate; (1S,2R)-N-(4-Methylphenylsulfonyl)ephedrine; (1S,2R)-Tosylephedrine; (1S,2R)-N-p-Toluenesulfonylephedrine
EINECS	Contact for details

Quality Control

Our (1S,2R)-n-Tosylephedrine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.