Description

Methanesulfonic Acid, Trifluoro-, 2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Ethyl Ester is a specialized fluorinated sulfonate ester derivative, valued for its role as a versatile building block and reagent in advanced synthetic chemistry. This compound is engineered to introduce the trifluoromethanesulfonate (triflate) group, a powerful leaving group, facilitating challenging nucleophilic substitution and cross-coupling reactions. It is primarily needed by research and development laboratories and fine chemical manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex, high-value molecules.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing functional groups or constructing complex heterocyclic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the triflate moiety is crucial for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical resistance properties.
• Ligand and Catalyst Preparation: Employed in organometallic chemistry for the preparation of metal complexes and catalysts used in asymmetric synthesis.
• Fluorine Chemistry: Acts as a stable source of the triflyl group in fluorination reactions and the synthesis of other fluorinated compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Methanesulfonic Acid, Trifluoro-, 2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Ethyl Ester
CAS No.	127175-39-7
Molecular Formula	C₁₁H₈F₃NO₄S
Molecular Weight	307.25 g/mol
Synonyms	2-(1,3-Dioxoisoindolin-2-yl)ethyl trifluoromethanesulfonate; N-(2-Triflyloxyethyl)phthalimide; 2-(Trifluoromethanesulfonyloxy)ethyl phthalimide; Phthalimidylethyl Triflate; 2-Phthalimidoethyl Triflate; Trifluoromethanesulfonic Acid 2-Phthalimidoethyl Ester; 1,3-Dihydro-1,3-dioxo-2H-isoindol-2-ylethyl Triflate
EINECS	Contact for details

Quality Control

Our Methanesulfonic Acid, Trifluoro-, 2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.