Description

Ethanone, 1-Bicyclo[2.2.1]Hept-2-Yl-2,2-Difluoro-, Exo- (9Ci) is a specialized difluorinated bicyclic ketone building block. This compound matters for its unique structural framework, which combines the rigidity of the norbornane skeleton with the electronic properties of a gem-difluoro ketone, enabling precise molecular design. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of complex drug candidates, particularly those requiring rigid, three-dimensional scaffolds with fluorine atoms for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the bicyclic structure and fluorine atoms can improve target binding and environmental persistence.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with unique thermal and chemical resistance properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands or metal complexes for asymmetric catalysis.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and the stereoelectronic effects of gem-difluoro groups in constrained ring systems.

Basic Information

Product Name	Ethanone, 1-Bicyclo[2.2.1]Hept-2-Yl-2,2-Difluoro-, Exo- (9Ci)
CAS No.	127119-03-3
Molecular Formula	C9H10F2O
Molecular Weight	172.17 g/mol
Synonyms	1-(exo-Bicyclo[2.2.1]hept-2-yl)-2,2-difluoroethan-1-one; 2,2-Difluoro-1-(2-norbornyl)ethanone, exo-; exo-1-Bicyclo[2.2.1]hept-2-yl-2,2-difluoroethanone; exo-2,2-Difluoro-1-(norborn-2-yl)ethanone; 1-(2-Norbornanyl)-2,2-difluoroethanone, exo-; Difluorinated Norbornyl Methyl Ketone; Norbornane-based Difluoro Ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-Bicyclo[2.2.1]Hept-2-Yl-2,2-Difluoro-, Exo- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by GC/HPLC), isomeric purity, and impurity profiles are available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
exo- Isomer Content	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.