Description

N,N'-Bis(2-Hydroxybenzyl)-1-(4-Bromoacetamidobenzyl)-1,2-Ethylenediamine-N,N'-Diacetic Acid is a sophisticated bifunctional chelating agent and synthetic intermediate of significant interest in advanced chemical research and development. Its molecular architecture, featuring a bromoacetamide group and multiple carboxylate donors, makes it a versatile precursor for creating targeted molecular probes and metal complexes. This compound is primarily utilized by researchers and manufacturers in the fields of medicinal chemistry, diagnostic imaging, and materials science who require high-purity, functionalized ligands for conjugation and chelation applications.

Application

• Radiopharmaceutical Precursor: Key intermediate for synthesizing bifunctional chelators used to label antibodies, peptides, or small molecules with diagnostic or therapeutic radionuclides (e.g., 99mTc, 111In, 177Lu).
• Contrast Agent Development: Building block for creating novel gadolinium(III) or other lanthanide-based complexes for Magnetic Resonance Imaging (MRI) contrast enhancement.
• Bioconjugation Linker: The reactive bromoacetamide moiety allows for selective covalent attachment to thiol groups (-SH) on proteins, antibodies, or other biomolecules for targeted delivery systems.
• Catalysis Research: Serves as a ligand scaffold for designing transition metal catalysts used in asymmetric synthesis or specialized organic transformations.
• Chemical Sensor Fabrication: Used in the development of fluorescent or colorimetric sensors for metal ion detection due to its strong metal-chelating properties.
• Polymer Functionalization: Intermediate for modifying polymer backbones to introduce metal-binding sites for creating functional materials or separation media.

Basic Information

Product Name	N,N'-Bis(2-Hydroxybenzyl)-1-(4-Bromoacetamidobenzyl)-1,2-Ethylenediamine-N,N'-Diacetic Acid
CAS No.	126926-47-4
Molecular Formula	C28H29BrN4O7
Molecular Weight	613.46 g/mol
Synonyms	1-(4-Bromoacetamidobenzyl)-N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid; HBED-CC-Br-AcNH-Bz; BrAcNH-Bz-HBED-CC; (4-Bromoacetamidobenzyl)-HBED-CC; N,N'-Bis(2-hydroxyphenylmethyl)-1-[(4-[(2-bromo-1-oxoethyl)amino]phenyl)methyl]-1,2-ethanediamine-N,N'-diacetic acid; Bifunctional HBED-CC Chelator (bromoacetamide derivative); HBED-CC-N-BrAc
EINECS	Contact for details

Quality Control

Our production of N,N'-Bis(2-Hydroxybenzyl)-1-(4-Bromoacetamidobenzyl)-1,2-Ethylenediamine-N,N'-Diacetic Acid adheres to stringent quality protocols suitable for research and development applications. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from HPLC, NMR, and mass spectrometry are provided to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.