Description

Ethanone, 1-[(1S,3R)-3-(Hydroxymethyl)-2,2-Dimethylcyclobutyl]- (9Ci) is a high-purity chiral cyclobutane derivative, a key building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable intermediate for creating complex molecules with specific biological activity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring stereochemical control.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, where its structural motif can contribute to specific biological targeting.
• Fine Chemical Production: Serves as a specialized building block in custom synthesis and the manufacture of high-value fine chemicals and flavors & fragrances.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, asymmetric synthesis, and catalysis studies.
• Material Science Precursor: Potential use in the synthesis of specialized monomers for polymers with unique thermal or mechanical properties.

Basic Information

Product Name	Ethanone, 1-[(1S,3R)-3-(Hydroxymethyl)-2,2-Dimethylcyclobutyl]- (9Ci)
CAS No.	126892-32-8
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	(1S,3R)-3-(Hydroxymethyl)-2,2-dimethylcyclobutyl methyl ketone; 1-[(1S,3R)-3-(Hydroxymethyl)-2,2-dimethylcyclobutyl]ethanone; (1S,3R)-2,2-Dimethyl-3-(hydroxymethyl)cyclobutan-1-yl methyl ketone; Chiral Cyclobutyl Methyl Ketone Derivative; (1S,3R)-3-(Acetylmethyl)-2,2-dimethylcyclobutanol (tautomer); 126892-32-8; (1S,3R)-rel-3-(Hydroxymethyl)-2,2-dimethylcyclobutan-1-yl methyl ketone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-[(1S,3R)-3-(Hydroxymethyl)-2,2-Dimethylcyclobutyl]- (9Ci) adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.