Description

2-(5-Chlorocarbonyl-2-Oxazolyl)-5,6-Methylenedioxybenzofuran (Omb-Cocl) is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzofuran-oxazole hybrid structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile reactive site for further chemical elaboration. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of proprietary active pharmaceutical ingredients (APIs) and investigational new drugs.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic frameworks and exploring new chemical entities.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation: The reactive chlorocarbonyl group enables its use in creating targeted conjugates for diagnostic or therapeutic applications.

Basic Information

Product Name	2-(5-Chlorocarbonyl-2-Oxazolyl)-5,6-Methylenedioxybenzofuran (Omb-Cocl)
CAS No.	126590-72-5
Molecular Formula	C13H6ClNO5
Molecular Weight	291.65 g/mol
Synonyms	Omb-Cocl; 5,6-Methylenedioxy-2-[5-(chlorocarbonyl)-1,3-oxazol-2-yl]benzofuran; 2-(5-Chloroformyl-2-oxazolyl)-5,6-methylenedioxybenzofuran; Benzofuran, 5,6-methylenedioxy-2-[5-(chlorocarbonyl)-2-oxazolyl]-; 126590-72-5
EINECS	Contact for details

Quality Control

Our 2-(5-Chlorocarbonyl-2-Oxazolyl)-5,6-Methylenedioxybenzofuran (Omb-Cocl) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.