Description

trans-4-T-Butoxy-5-Hydroxy-2-Cyclopenten-1-One is a high-value, chiral cyclopentenone derivative that serves as a critical synthetic intermediate. Its unique structure, featuring both a protected hydroxyl group and a reactive ketone, makes it an essential building block for the stereoselective synthesis of complex organic molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and fine chemical industries for constructing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, nucleoside analogs, and other bioactive molecules with defined stereochemistry.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, flavors, and fragrances where precise stereocontrol is required.
• Academic & Industrial Research: Serves as a versatile starting material in methodological development for new asymmetric synthesis routes.
• Agrochemical Development: Potential intermediate in creating novel, stereospecific pesticides and plant growth regulators.
• Material Science Precursor: Can be utilized in the synthesis of specialized polymers and liquid crystals.

Basic Information

Product Name	trans-4-T-Butoxy-5-Hydroxy-2-Cyclopenten-1-One
CAS No.	126566-41-4
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	trans-4-(tert-Butoxy)-5-hydroxy-2-cyclopenten-1-one; 4-(tert-Butoxy)-5-hydroxy-2-cyclopenten-1-one; 5-Hydroxy-4-(tert-butoxy)-2-cyclopenten-1-one; (4R,5S)-4-(tert-Butoxy)-5-hydroxy-2-cyclopenten-1-one (for specific enantiomer); TBHCP; tert-Butoxy Hydroxy Cyclopentenone
EINECS	Contact for details

Quality Control

Our trans-4-T-Butoxy-5-Hydroxy-2-Cyclopenten-1-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, chiral purity (enantiomeric excess), and identity confirmation (IR, NMR). Certificates of Analysis (COA) detailing all specifications are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.