Description

2-Methylpropylzinc Bromide is a highly reactive organozinc reagent, specifically an alkylzinc halide, widely utilized in organic synthesis. Its primary value lies in its role as a versatile nucleophile for the formation of carbon-carbon bonds, particularly in cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and efficient synthetic methodologies.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the isobutyl group into complex molecules during drug discovery and development.
• Negishi Cross-Coupling Reactions: Used as a critical reagent with palladium catalysts to couple with various organic electrophiles, constructing new C-C bonds.
• Agrochemical Production: Employed in the synthesis of active ingredients and fine chemicals for crop protection products.
• Materials Science Research: Facilitates the creation of novel organic compounds and polymers with tailored properties.
• Catalyst and Ligand Development: Serves as a precursor in the preparation of specialized zinc-based catalysts and organometallic complexes.
• Laboratory-Scale Organic Synthesis: Provides a reliable and selective tool for academic and industrial R&D chemists exploring new synthetic routes.

Basic Information

Product Name	2-Methylpropylzinc Bromide
CAS No.	126403-67-6
Molecular Formula	C4H9BrZn
Molecular Weight	202.41 g/mol
Synonyms	Isobutylzinc Bromide; (2-Methylpropyl)zinc Bromide; Zinc, bromo(2-methylpropyl)-; Bromo(isobutyl)zinc; Iso-BuZnBr
EINECS	Contact for details

Quality Control

Our 2-Methylpropylzinc Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes comprehensive analysis, including titration for active zinc content and spectroscopic identification. Certificates of Analysis (COA) detailing purity and specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C. Handle and open containers only under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration (in solvent)	Typically 0.5 M to 1.0 M in THF or Diethyl Ether
Assay (by Titration)	≥ 95% (as RZnBr)
Identification (IR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.