Description

(4R,6R)-6-(2-Aminoethyl)-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid CAS NO 125995-17-7 is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its stereochemically defined structure, which is critical for producing enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development and production of complex therapeutic agents.

Application

• Key chiral building block for the synthesis of statin-class pharmaceuticals and other complex drug molecules.
• Advanced pharmaceutical intermediate in the production of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Research and development of novel therapeutic compounds in medicinal chemistry.
• Process chemistry for scaling up the manufacture of high-value fine chemicals.
• Asymmetric synthesis catalyst or ligand precursor in specialized organic reactions.
• Reference standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Item	Details
Product Name	(4R,6R)-6-(2-Aminoethyl)-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid
CAS No.	125995-17-7
Molecular Formula	C₁₀H₁₉NO₄
Molecular Weight	217.26 g/mol
Synonyms	(4R-cis)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid; (4R,6R)-Atorvastatin Lactone Intermediate; (4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid; (4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid; (4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid; (4R,6R)-Atorvastatin Lactone Precursor; (4R,6R)-Dioxane Acetic Acid Derivative
EINECS	Contact for details

Quality Control

Our (4R,6R)-6-(2-Aminoethyl)-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical assay, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (4R,6R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.