Description

(R)-Lindenether,2,4,5,7A-Tetrahydro-3,6-Dimethyl-Benzofuran is a chiral, non-racemic compound belonging to the class of substituted benzofurans, which are valuable synthetic intermediates and building blocks in organic chemistry. Its specific stereochemistry makes it a crucial precursor for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors where enantiomeric purity is paramount. This high-value intermediate is essential for research and development chemists, process chemists, and manufacturers in fine chemical, pharmaceutical, and flavor & fragrance industries seeking to develop novel active ingredients with defined stereochemistry.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and anti-inflammatory drug research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, where the specific (R)-configuration can influence biological activity and environmental degradation.
• Flavor & Fragrance Chemistry: Serves as a precursor for creating specific, high-value aroma chemicals and flavorants with desired olfactory profiles.
• Academic & Industrial R&D: A valuable tool for methodological development in asymmetric synthesis, catalysis studies, and exploring new reaction pathways.
• Material Science Precursor: Potential use in the synthesis of specialized organic ligands for catalysis or advanced organic materials.

Basic Information

Item	Details
Product Name	(R)-Lindenether,2,4,5,7A-Tetrahydro-3,6-Dimethyl-Benzofuran
CAS No.	125811-37-2
Molecular Formula	C11H16O
Molecular Weight	164.24 g/mol
Synonyms	(R)-2,4,5,7a-Tetrahydro-3,6-dimethylbenzofuran; (R)-Linden Ether; (R)-3,6-Dimethyl-2,4,5,7a-tetrahydrobenzofuran; (R)-Tetrahydrodimethylbenzofuran; (R)-THDBF; (R)-Lindenether; (R)-2,3-Dihydro-3,6-dimethylbenzofuran (related structure); (R)-Hexahydrodimethylbenzofuran derivative
EINECS	Contact for details

Quality Control

Every batch of (R)-Lindenether,2,4,5,7A-Tetrahydro-3,6-Dimethyl-Benzofuran is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure high enantiomeric excess (e.e.) and chemical purity, critical for your asymmetric synthesis workflows. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay, chiral purity by chiral HPLC or GC, and identification by spectroscopic methods (NMR, IR).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its properties of being easily oxidized and highly volatile, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to minimize evaporation and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.