Description

2-Butanone, 3-Bicyclo[1.1.1]Pent-1-Yl- (9Ci) is a specialized organic compound featuring a unique bicyclo[1.1.1]pentane scaffold, a structure of significant interest in modern medicinal and materials chemistry for its role as a bioisostere. This compound matters for its ability to impart favorable physicochemical properties, such as reduced conformational flexibility and improved metabolic stability, when incorporated into molecular frameworks. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for use as a key synthetic intermediate or building block.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for creating three-dimensional, sp3-rich carbon centers.
• Agrochemical Research: Used in the development of new crop protection agents and herbicides, where the bicyclo[1.1.1]pentane moiety can enhance biological activity and environmental profile.
• Materials Science: Acts as a precursor for monomers or cross-linkers in the production of polymers with unique mechanical or optical properties.
• Chemical Biology & Probe Development: Employed in the design of molecular probes and tool compounds for studying biological systems and target engagement.
• Organic Synthesis: Functions as a versatile reagent for introducing sterically constrained, bridgehead functional groups in complex molecule synthesis.

Basic Information

Product Name	2-Butanone, 3-Bicyclo[1.1.1]Pent-1-Yl- (9Ci)
CAS No.	125642-50-4
Molecular Formula	C9H14O
Molecular Weight	138.21 g/mol
Synonyms	3-(Bicyclo[1.1.1]pentan-1-yl)butan-2-one; 1-(Bicyclo[1.1.1]pent-1-yl)-2-butanone; 3-Bicyclo[1.1.1]pent-1-yl-2-butanone; Bicyclo[1.1.1]pentane-1-butanone derivative; BCP-butanone; [1.1.1]Propellane derivative ketone
EINECS	Contact for details

Quality Control

Our 2-Butanone, 3-Bicyclo[1.1.1]Pent-1-Yl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR, MS), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We support development and scale-up with custom purity grades to meet specific research and cGMP needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥95.0% (Standard Grade)
Purity (GC/HPLC)	≥98.0% (High Purity Grade)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.