Description

2-Bromo-1-(4-Chlorophenyl)Ethylene is a versatile halogenated styrene derivative, a key synthetic intermediate prized for its reactive vinyl bromide moiety. This compound matters for enabling precise carbon-carbon bond formation in complex molecule assembly, offering chemists a critical handle for cross-coupling and functionalization reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing active ingredients and novel organic frameworks.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the 4-chlorophenyl group contributes to biological activity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and functionalized materials.
• Organic Synthesis Reagent: Employed in Heck-type cross-coupling reactions, Suzuki-Miyaura couplings, and other palladium-catalyzed transformations to introduce arylvinyl groups.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing novel phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.
• Chemical Research: Utilized in academic and industrial R&D for exploring new synthetic methodologies and constructing molecular libraries for screening.

Basic Information

Product Name	2-Bromo-1-(4-Chlorophenyl)Ethylene
CAS No.	125428-11-7
Molecular Formula	C8H6BrCl
Molecular Weight	217.49 g/mol
Synonyms	1-(4-Chlorophenyl)-2-bromoethene; (2-Bromovinyl)-4-chlorobenzene; 4-Chloro-β-bromostyrene; 2-Bromo-1-(4-chlorophenyl)ethene; 4-Chlorostyryl Bromide; β-Bromo-4-chlorostyrene; 1-Bromo-2-(4-chlorophenyl)ethylene; (E/Z)-2-Bromo-1-(4-chlorophenyl)ethylene
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(4-Chlorophenyl)Ethylene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.