Description

Ethanone, 1-[(1R,2R)-1,2-Dihydroxy-3-Cyclohexen-1-Yl]-, Rel- (9Ci) is a chiral, enantiomerically defined organic compound featuring a cyclohexene ring with vicinal diol and acetyl functionalities. This specific stereochemistry makes it a valuable chiral building block and intermediate for the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring stereochemical control.
• Asymmetric Synthesis: Used as a starting material or precursor in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in the discovery and optimization of drug candidates, leveraging its defined stereocenters to explore structure-activity relationships.
• Fine Chemical Synthesis: Serves as a specialized intermediate for producing high-value agrochemicals, flavors, fragrances, and advanced materials.
• Academic & R&D Laboratories: Utilized in methodological studies and the development of new synthetic organic chemistry protocols.

Basic Information

Product Name	Ethanone, 1-[(1R,2R)-1,2-Dihydroxy-3-Cyclohexen-1-Yl]-, Rel- (9Ci)
CAS No.	125229-00-7
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(1R,2R)-1-Acetyl-1,2-dihydroxycyclohex-3-ene; rel-(1R,2R)-1-Acetyl-1,2-dihydroxy-3-cyclohexene; 1-[(1R,2R)-1,2-Dihydroxy-3-cyclohexen-1-yl]ethanone; (rel)-(1R,2R)-1-Acetyl-1,2-dihydroxycyclohex-3-ene; Chiral Cyclohexene Diol Acetate; 3-Cyclohexene-1,2-diol, 1-acetyl-, (1R,2R)-rel-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC) and can offer custom synthesis to meet specific enantiomeric excess (ee) requirements. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are available upon request. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.