Description

1,3-Dioxolane-4-Carboxylicacid,2,2,5-Trimethyl-,(4S-Cis)-(9Ci) is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined structure, which is crucial for imparting specific biological activity in final target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereochemistry is a critical design parameter.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly where the dioxolane moiety is integral to the drug's structure.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific isomer can affect potency and environmental profile.
• Asymmetric Catalysis & Ligand Development: Serves as a precursor for chiral ligands or catalysts used in enantioselective synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for electronics or material science applications.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, particularly in reactions involving protected carboxylic acid derivatives.

Basic Information

Item	Details
Product Name	1,3-Dioxolane-4-Carboxylicacid,2,2,5-Trimethyl-,(4S-Cis)-(9Ci)
CAS No.	124600-38-0
Molecular Formula	C8H14O4
Molecular Weight	174.19 g/mol
Synonyms	(4S-cis)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxylic acid; (4S,5S)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxylic acid; (4S,5S)-2,2,5-Trimethyl-[1,3]dioxolane-4-carboxylic acid; (4S,5S)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxylic Acid; cis-2,2,5-Trimethyl-1,3-dioxolane-4-carboxylic Acid (4S); 1,3-Dioxolane-4-carboxylic acid, 2,2,5-trimethyl-, (4S-cis)-
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxylicacid,2,2,5-Trimethyl-,(4S-Cis)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for the specific grade.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.