Description

Benzoic Acid, 3-(Fluorosulfonyl)-, Methyl Ester is a specialized fluorosulfonyl-containing aromatic ester, a key building block in advanced organic synthesis. Its unique structure, featuring both an ester and a highly reactive fluorosulfonyl group, makes it a versatile intermediate for introducing sulfonyl fluoride functionalities into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with sulfonyl fluoride moieties.
• Chemical Biology & Proteomics: Serves as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent inhibitors.
• Material Science: Employed in the synthesis of specialty polymers and advanced materials with specific surface functionalities.
• Sulfonyl Fluoride Chemistry: A fundamental reagent for SuFEx (Sulfur Fluoride Exchange) click chemistry, enabling robust and selective ligations.
• Custom Synthesis & R&D: Provides a versatile scaffold for medicinal chemistry and process research in contract development and manufacturing organizations (CDMOs).

Basic Information

Product Name	Benzoic Acid, 3-(Fluorosulfonyl)-, Methyl Ester
CAS No.	124397-36-0
Molecular Formula	C8H7FO4S
Molecular Weight	218.20 g/mol
Synonyms	3-(Fluorosulfonyl)benzoic acid methyl ester; Methyl 3-(fluorosulfonyl)benzoate; Methyl 3-fluorosulfonylbenzoate; 3-Fluorosulfonylbenzoic Acid Methyl Ester; Benzoic acid, 3-(fluorosulfonyl)-, methyl ester; Methyl m-fluorosulfonylbenzoate; 3-(Fluorosulphonyl)benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 3-(Fluorosulfonyl)-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its reactivity as a strong acid/organic solvent derivative, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents. Keep the container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.