Description

2H-1-Benzopyran-2-Carboxylic Acid, 3,4-Dihydro-7-Hydroxy-, (S)- is a high-purity chiral intermediate of significant interest in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in stereoselective synthesis to construct complex molecular architectures with high enantiomeric purity.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Biochemical Research: Used in academic and industrial research to study enzyme interactions, receptor binding, and other structure-activity relationships (SAR).
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	2H-1-Benzopyran-2-Carboxylic Acid, 3,4-Dihydro-7-Hydroxy-, (S)-
CAS No.	124356-21-4
Molecular Formula	C10H10O4
Molecular Weight	194.18 g/mol
Synonyms	(S)-7-Hydroxy-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid; (S)-7-Hydroxy-chroman-2-carboxylic acid; (S)-7-Hydroxy-2-carboxychroman; (S)-7-Hydroxy-2-chromancarboxylic acid; (S)-7-Hydroxy-3,4-dihydrocoumarin-2-carboxylic acid; (S)-7-Hydroxy-3,4-dihydro-2H-chromene-2-carboxylic acid; (S)-7-Hydroxy-3,4-dihydro-1-benzopyran-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-2-Carboxylic Acid, 3,4-Dihydro-7-Hydroxy-, (S)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.