Description

n-Adamanty-1-Yl-N'-(2-Iodophenyl)Guanidine is a high-purity, functionalized guanidine derivative featuring a rigid adamantane scaffold and an ortho-iodophenyl substituent. This unique molecular architecture makes it a valuable intermediate and building block for advanced organic synthesis, particularly in the development of novel pharmaceutical candidates and specialty materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science sectors for creating compounds with targeted biological activity or specific physical properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets, due to the lipophilic adamantane group enhancing blood-brain barrier penetration.
• Agrochemical Research: Used in developing novel active ingredients for crop protection, where the guanidine moiety can impart herbicidal or fungicidal properties.
• Material Science Building Block: Employed in the creation of advanced polymers, ligands for catalysis, or organic frameworks where the iodine atom allows for further functionalization via cross-coupling reactions.
• Chemical Biology Probe: Acts as a scaffold for designing molecular probes to study biological processes, leveraging the iodine for radiolabeling (e.g., with I-125) or as a handle for bioconjugation.
• Catalyst Ligand Development: The guanidine group can be utilized to develop novel ligands for metal complexes used in asymmetric synthesis.

Basic Information

Product Name	n-Adamanty-1-Yl-N'-(2-Iodophenyl)Guanidine
CAS No.	124190-30-3
Molecular Formula	C₁₇H₂₂IN₃
Molecular Weight	395.28 g/mol
Synonyms	1-Adamantyl-N'-(2-iodophenyl)guanidine; N-(1-Adamantyl)-N'-(2-iodophenyl)guanidine; 1-(Adamantan-1-yl)-3-(2-iodophenyl)guanidine; Guanidine, N-(1-adamantyl)-N'-(2-iodophenyl)-; Adamantyl(2-iodophenyl)guanidine; 124190-30-3; N-Adamantyl-N'-(2-iodophenyl)guanidine
EINECS	Contact for details

Quality Control

Our n-Adamanty-1-Yl-N'-(2-Iodophenyl)Guanidine is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested to meet rigorous in-house specifications suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.