Description

Ivermectin B1a Monosaccharide is a key monosaccharide derivative and a primary building block in the synthesis of the potent antiparasitic agent, Ivermectin. This high-purity intermediate is critical for ensuring the efficacy and consistency of the final active pharmaceutical ingredient (API). It is essential for manufacturers in the pharmaceutical and veterinary medicine sectors who require reliable, high-quality raw materials for producing antiparasitic treatments.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of Ivermectin API for human and veterinary use.
• Veterinary Drug Manufacturing: Essential for producing endectocides used to treat parasites in livestock and companion animals.
• Research & Development: Serves as a reference standard and starting material for developing new macrocyclic lactone derivatives and studying structure-activity relationships.
• Active Pharmaceutical Ingredient (API) Synthesis: A fundamental component in multi-step synthesis pathways under current Good Manufacturing Practice (cGMP) conditions.
• Biochemical Research: Used in studies investigating the mode of action of avermectins on invertebrate nerve and muscle cells.

Basic Information

Item	Details
Product Name	Ivermectin B1a Monosaccharide
CAS No.	123997-64-8
Molecular Formula	C48H74O14
Molecular Weight	875.1 g/mol
Synonyms	5-O-Demethyl-28-deoxy-25-de(1-methylpropyl)-6,28-epoxy-23-(methoxycarbonyl)-12,13-didehydro-4''-deoxy-4''-(methylamino)avermectin A1a aglycone; Ivermectin B1a monosaccharide; 4''-Deoxy-4''-(methylamino)avermectin B1a; 4''-Epimethylamino-4''-deoxyavermectin B1a; Avermectin B1a monosaccharide derivative; MK-0936 monosaccharide
EINECS	Contact for details

Quality Control

Our Ivermectin B1a Monosaccharide is produced and tested to meet exacting standards suitable for pharmaceutical synthesis. Quality is assured through rigorous analytical controls including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all critical parameters. Production can be aligned with cGMP guidelines upon request to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.