Description

Ivermectin Aglycone is a key chemical intermediate derived from the macrocyclic lactone family, representing the core structural moiety of the widely used antiparasitic agent, Ivermectin. This compound is of significant value for research and development in the pharmaceutical and agrochemical sectors, serving as a versatile building block for novel synthetic derivatives. It is primarily sought by manufacturers and research institutions engaged in the development of new therapeutic agents, veterinary medicines, and crop protection products.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel antiparasitic and potentially antiviral drug candidates.
• Veterinary Medicine Research: Used in R&D for developing next-generation treatments for parasitic infections in livestock and companion animals.
• Agrochemical Development: Acts as a starting material for creating new, potent insecticides and acaricides with improved efficacy.
• Biochemical Research: Employed in studies to understand the mechanism of action of macrocyclic lactones and their interactions with biological targets.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for the identification and quantification of related compounds.
• Custom Synthesis: Provides a foundational structure for contract research organizations (CROs) and pharmaceutical companies for custom chemical synthesis projects.

Basic Information

Product Name	Ivermectin Aglycone
CAS No.	123997-59-1
Molecular Formula	C48H74O14
Molecular Weight	875.1 g/mol
Synonyms	22,23-Dihydroavermectin B1a aglycone; 5-O-Demethyl-22,23-dihydroavermectin A1a aglycone; Ivermectin Hydrolysis Product; Ivermectin Aglycon; Avermectin B1a, 22,23-dihydro-, aglycone; 4"-Deoxy-4"-epi-acetylamino-22,23-dihydroavermectin B1 aglycone
EINECS	Contact for details

Quality Control

Our Ivermectin Aglycone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.