Description

7,7-Dimethyl-2-Oxo-5,8-Dihydro-1H-Pyrano[4,3-B]Pyridine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused pyranopyridine core structure. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of novel therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Reagent: Employed in the construction of complex polycyclic frameworks due to its reactive nitrile and carbonyl functionalities.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel active ingredients for crop protection products.
• Academic & Industrial R&D: Utilized in chemical research laboratories for methodological development and the exploration of new chemical spaces.

Basic Information

Item	Details
Product Name	7,7-Dimethyl-2-Oxo-5,8-Dihydro-1H-Pyrano[4,3-B]Pyridine-3-Carbonitrile
CAS No.	123990-47-6
Molecular Formula	C11H10N2O2
Molecular Weight	202.21 g/mol
Synonyms	7,7-Dimethyl-2-oxo-1,5,8,8a-tetrahydro-2H-pyrano[4,3-b]pyridine-3-carbonitrile; 7,7-Dimethyl-2-oxo-5,8-dihydro-2H-pyrano[4,3-b]pyridine-3-carbonitrile; 3-Cyano-7,7-dimethyl-5,8-dihydro-1H-pyrano[4,3-b]pyridin-2-one; Pyrano[4,3-b]pyridine-3-carbonitrile, 5,8-dihydro-7,7-dimethyl-2-oxo-1H-; CAS 123990-47-6
EINECS	Contact for details

Quality Control

Our 7,7-Dimethyl-2-Oxo-5,8-Dihydro-1H-Pyrano[4,3-B]Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.