Description

(R)-(-)-Glycidyl-4-Nitrobenzenesulfonate is a high-purity chiral building block and electrophilic epoxide reagent. This compound is valued for its role in the stereoselective synthesis of complex molecules, enabling the introduction of functionalized chiral centers. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis, medicinal chemistry, and the development of active pharmaceutical ingredients (APIs).

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key reagent for the stereospecific construction of β-blockers, antiviral agents, and other chiral drugs.
• Asymmetric Catalysis Research: Used in academic and industrial R&D to develop new catalytic methodologies and chiral ligands.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.
• Derivatization Agent: Acts as an electrophile for nucleophilic ring-opening reactions with amines, alcohols, and thiols to create novel molecular scaffolds.
• Polymer Modification: Can be used to introduce reactive epoxy and sulfonate functionalities into polymers for advanced material science applications.

Basic Information

Product Name	(R)-(-)-Glycidyl-4-Nitrobenzenesulfonate
CAS No.	123750-60-7
Molecular Formula	C9H9NO6S
Molecular Weight	259.24 g/mol
Synonyms	(R)-Glycidyl 4-nitrobenzenesulfonate; (R)-(-)-Glycidyl tosylate analog; (R)-Epoxypropyl 4-nitrobenzenesulfonate; (2R)-(-)-Glycidyl 4-nitrobenzenesulfonate; (R)-Oxiran-2-ylmethyl 4-nitrobenzenesulfonate; 4-Nitrobenzenesulfonic acid (2R)-oxiranylmethyl ester; (R)-ENBS
EINECS	Contact for details

Quality Control

Our (R)-(-)-Glycidyl-4-Nitrobenzenesulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP standards where applicable, ensuring reliability for critical research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.