Description

Pyridine, 4-Chloro-3-(Triethylsilyl)- (9Ci) is a specialized organosilicon-substituted pyridine derivative, serving as a valuable synthetic intermediate. Its molecular architecture, featuring both a halogen and a silyl protecting group, makes it a versatile building block for constructing complex molecules in advanced research and development. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the pyridine core is a common bioactive motif.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of advanced organic electronic materials and silicon-containing polymers.
• Cross-Coupling Reactions: The chloro and silyl groups offer orthogonal reactivity for sequential functionalization via Suzuki, Stille, or Hiyama-type cross-couplings.
• Protecting Group Strategy: The triethylsilyl group can act as a protecting group for alcohols or other functionalities in multi-step synthetic sequences.

Basic Information

Product Name	Pyridine, 4-Chloro-3-(Triethylsilyl)- (9Ci)
CAS No.	123506-94-5
Molecular Formula	C13H22ClNSi
Molecular Weight	255.86 g/mol
Synonyms	4-Chloro-3-(triethylsilyl)pyridine; 3-(Triethylsilyl)-4-chloropyridine; 4-Chloro-3-triethylsilylpyridine; 4-Chloro-3-(triethylsilyl)pyridine (9CI); 4-Chloro-3-(triethylsilyl)pyridine, 9CI; Pyridine, 4-chloro-3-(triethylsilyl)-; 123506-94-5
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 4-Chloro-3-(Triethylsilyl)- (9Ci) is produced and analyzed under strict quality management protocols to ensure consistency and purity for research applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the high standards required for synthetic chemistry. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.