Description

3,4-Dihydro-2H-1,4-Benzoxazine-5-Carboxylic Acid is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core benzoxazine scaffold makes it a critical intermediate for developing novel pharmaceuticals and agrochemicals. This compound is primarily sought after by research and development chemists in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a monomer or building block for developing advanced polymers and functional materials.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	3,4-Dihydro-2H-1,4-Benzoxazine-5-Carboxylic Acid
CAS No.	123296-71-9
Molecular Formula	C9H9NO3
Molecular Weight	179.17 g/mol
Synonyms	5-Carboxy-3,4-dihydro-2H-1,4-benzoxazine; 2H-1,4-Benzoxazine-5-carboxylic acid, 3,4-dihydro-; 3,4-Dihydro-2H-benzo[b][1,4]oxazine-5-carboxylic acid; 1,4-Benzoxazine-5-carboxylic acid, 3,4-dihydro-2H-; DHBOCA
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-2H-1,4-Benzoxazine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.