Description

[4S-(4α,7β,7Aα)]-7,7A-Dihydro-7-Hydroxy-4-Methoxy-4H-Furo[3,2-C]Pyran-2(6H)-One is a high-purity, stereochemically defined heterocyclic compound that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique fused furopyranone structure makes it valuable for constructing complex molecular architectures with precise stereochemical control. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in antiviral, anticancer, and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Used as a precursor in the synthesis of advanced, biologically active molecules for crop protection and pest management.
• Academic & Industrial Research: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural product analogs and specialty performance chemicals.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing catalytic asymmetric transformations in pilot plants.

Basic Information

Product Name	[4S-(4α,7β,7Aα)]-7,7A-Dihydro-7-Hydroxy-4-Methoxy-4H-Furo[3,2-C]Pyran-2(6H)-One
CAS No.	123251-08-1
Molecular Formula	C9H10O5
Molecular Weight	198.17 g/mol
Synonyms	(4S,7R,7aS)-7-Hydroxy-4-methoxy-4,7,7a,8-tetrahydro-2H-furo[3,2-c]pyran-2-one; 7-Hydroxy-4-methoxy-4,7,7a,8-tetrahydro-2H-furo[3,2-c]pyran-2-one (4S,7R,7aS)-; 4-Methoxy-7-hydroxy-4,7,7a,8-tetrahydro-2H-furo[3,2-c]pyran-2-one; Furo[3,2-c]pyran-2-one derivative; Chiral furopyranone intermediate; CAS 123251-08-1
EINECS	Contact for details

Quality Control

Every batch of [4S-(4α,7β,7Aα)]-7,7A-Dihydro-7-Hydroxy-4-Methoxy-4H-Furo[3,2-C]Pyran-2(6H)-One is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and stereochemical integrity. Our quality commitment includes HPLC purity verification, chiral purity analysis, and full spectroscopic characterization (NMR, IR, MS). A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.