Description

(Cis)2-Iodocyclopropanecarboxylic Acid is a high-value, stereochemically defined iodinated cyclopropane building block. This compound matters for its unique reactivity profile, enabling the synthesis of complex, strained-ring molecular architectures that are difficult to access via other routes. It is primarily needed by pharmaceutical research and fine chemical synthesis teams for developing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly those incorporating cyclopropane motifs for metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide molecules where the cyclopropane ring enhances biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and functional materials with unique structural properties.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in metal-catalyzed reactions (e.g., Negishi, Suzuki) to introduce the cyclopropane fragment.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the exploration of new reaction pathways.

Basic Information

Product Name	(Cis)2-Iodocyclopropanecarboxylic Acid
CAS No.	122676-92-0
Molecular Formula	C4H5IO2
Molecular Weight	211.99 g/mol
Synonyms	(1R,2S)-2-Iodocyclopropanecarboxylic Acid; (1S,2R)-2-Iodocyclopropanecarboxylic Acid; cis-2-Iodocyclopropanecarboxylic Acid; rel-(1R,2S)-2-Iodocyclopropanecarboxylic Acid; 2-Iodocyclopropanecarboxylic Acid, cis-; Cyclopropanecarboxylic acid, 2-iodo-, cis-; 2-Iodo-1-cyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our (Cis)2-Iodocyclopropanecarboxylic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and stereochemical integrity, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.