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(R)-[1,1']Binaphthalenyl-2,2'-Disulfonic Acid CAS NO 122361-59-5


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CAS No.:122361-59-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-[1,1']Binaphthalenyl-2,2'-Disulfonic Acid is a high-purity, chiral binaphthyl derivative that serves as a critical building block and resolving agent in asymmetric synthesis. Its value lies in its strong acidic character and rigid, enantiomerically pure backbone, which is essential for inducing chirality in complex organic molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and chiral catalysts.

Application

  • Chiral Resolution Agent: Used for the separation of enantiomers in racemic mixtures, particularly for amines and other basic compounds.
  • Asymmetric Catalysis: Acts as a precursor or co-catalyst for chiral Brønsted acid catalysts in stereoselective transformations.
  • Pharmaceutical Intermediate: A key synthon in the synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
  • Ligand Synthesis: Serves as a foundational structure for creating novel chiral ligands used in metal-catalyzed reactions.
  • Analytical Chemistry: Employed as a chiral selector or mobile phase additive in High-Performance Liquid Chromatography (HPLC) for analytical separations.
  • Agrochemical Research: Utilized in the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
  • Materials Science: Investigated for the creation of chiral polymers and functional materials with specific optical properties.

Basic Information

Product Name (R)-[1,1']Binaphthalenyl-2,2'-Disulfonic Acid
CAS No. 122361-59-5
Molecular Formula C₂₀H₁₄O₆S₂
Molecular Weight 414.45 g/mol
Synonyms (R)-1,1'-Binaphthyl-2,2'-disulfonic Acid; (R)-BINSA; (R)-BINOL Disulfonic Acid; (R)-2,2'-Dihydroxy-1,1'-binaphthyl-6,6'-disulfonic Acid; (R)-6,6'-Dibromo-2,2'-dihydroxy-1,1'-binaphthyl-4,4'-disulfonic Acid (related derivative); (R)-BINOL-6,6'-disulfonic Acid; (R)-BINOL-DSA; (R)-1,1'-Bi-2-naphthol-6,6'-disulfonic Acid
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Quality Control

Our (R)-[1,1']Binaphthalenyl-2,2'-Disulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with high-purity standards for research and synthesis. Certificates of Analysis (COA) detailing specific results for chiral purity, chemical purity, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Chiral Purity (Enantiomeric Excess) ≥ 99.0% ee (by HPLC)
Assay (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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