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(R,R)-N,N'-Bis(Trifluoromethanesulfonyl)-1,2-Diphenylethylenediamine CAS NO 121788-73-6
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CAS No.:121788-73-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R,R)-N,N'-Bis(Trifluoromethanesulfonyl)-1,2-Diphenylethylenediamine is a high-purity, chiral sulfonamide derivative that serves as a critical ligand and catalyst precursor in advanced asymmetric synthesis. Its value lies in enabling highly enantioselective transformations, which are essential for producing single-isomer active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel chiral compounds and process optimization.
Application
- As a chiral ligand for transition metal catalysts in asymmetric hydrogenation and carbon-carbon bond-forming reactions.
- As a key intermediate or catalyst precursor in the synthesis of enantiomerically pure pharmaceutical actives.
- For use in academic and industrial R&D focused on developing new asymmetric catalytic methodologies.
- In the preparation of high-value specialty chemicals and agrochemical intermediates requiring specific chirality.
- As a standard or reference material for analytical method development in chiral separation techniques (e.g., HPLC, SFC).
- For scale-up process development in contract manufacturing organizations (CMOs) serving the pharma and biotech industries.
Basic Information
| Product Name | (R,R)-N,N'-Bis(Trifluoromethanesulfonyl)-1,2-Diphenylethylenediamine |
| CAS No. | 121788-73-6 |
| Molecular Formula | C₁₆H₁₄F₆N₂O₄S₂ |
| Molecular Weight | 476.42 g/mol |
| Synonyms | (R,R)-TsDPEN; (R,R)-N,N'-Bis(triflyl)-1,2-diphenylethylenediamine; (R,R)-N,N'-Bis(trifluoromethanesulfonyl)-1,2-diamino-1,2-diphenylethane; (R,R)-DPEN-Tf₂; (1R,2R)-N,N'-Bis[(trifluoromethyl)sulfonyl]-1,2-diphenyl-1,2-ethanediamine; (R,R)-1,2-Diphenyl-N,N'-bis[(trifluoromethyl)sulfonyl]ethane-1,2-diamine; (R,R)-BISTFI-DPEN; Chiral Triflyl-DPEN Ligand |
| EINECS | Contact for details |
Quality Control
Our (R,R)-N,N'-Bis(Trifluoromethanesulfonyl)-1,2-Diphenylethylenediamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for catalytic and synthetic applications. A detailed Certificate of Analysis (COA) providing purity, chiral excess, and impurity profile is supplied with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect performance. For long-term storage, consider using desiccants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity (Chiral HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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