Description

2-Pentanone, 1,1,1-Trifluoro-5-Hydroxy- is a specialized fluorinated ketone derivative that serves as a valuable building block in advanced organic synthesis. Its unique structure, featuring both a trifluoromethyl group and a hydroxyl function, makes it a versatile intermediate for introducing fluorine atoms into target molecules, which can dramatically alter their physical, chemical, and biological properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, including protease inhibitors, kinase inhibitors, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group improves efficacy and environmental profile.
• Material Science Research: Serves as a precursor for fluorinated monomers or additives aimed at creating polymers with special properties like oil/water repellency, chemical resistance, or low surface energy.
• Liquid Crystal & Electronic Chemicals: Potential intermediate in the synthesis of fluorinated components for liquid crystal displays (LCDs) and other electronic materials.
• Organic Synthesis & Methodology Development: A valuable substrate for exploring new fluorination reactions and catalytic processes in academic and industrial R&D settings.

Basic Information

Product Name	2-Pentanone, 1,1,1-Trifluoro-5-Hydroxy-
CAS No.	121749-66-4
Molecular Formula	C5H7F3O2
Molecular Weight	156.10 g/mol
Synonyms	5-Hydroxy-1,1,1-trifluoro-2-pentanone; 1,1,1-Trifluoro-5-hydroxypentan-2-one; 5-Hydroxy-1,1,1-trifluoropentan-2-one; 5-Hydroxy-1,1,1-trifluoro-2-oxopentane; 1,1,1-Trifluoro-5-hydroxy-2-pentanone; Trifluoromethyl hydroxy ketone intermediate
EINECS	Contact for details

Quality Control

Every batch of 2-Pentanone, 1,1,1-Trifluoro-5-Hydroxy- is produced and tested under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of hydroxyl and carbonyl functional groups, it should be kept separate from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.