Description

Ethanone, 1-(4,4-Difluorocyclohexyl)- (9Ci) is a high-purity fluorinated ketone building block of significant interest in advanced organic synthesis. This compound is valued for its unique structural motif, which incorporates a difluorocyclohexyl group, offering enhanced metabolic stability and lipophilicity to target molecules. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients. Its precise synthesis and reliable supply are essential for driving innovation in life science applications.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the difluorocyclohexyl moiety can improve efficacy and environmental profile.
• Material Science Research: Employed as a monomer or precursor for developing specialty polymers with tailored properties like chemical resistance and low surface energy.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing compounds used in electronic display technologies.
• Fluorine Chemistry & Catalysis: Acts as a valuable substrate in academic and industrial research exploring new fluorination methodologies and catalytic processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke fine chemicals and APIs.

Basic Information

Product Name	Ethanone, 1-(4,4-Difluorocyclohexyl)- (9Ci)
CAS No.	121629-16-1
Molecular Formula	C8H12F2O
Molecular Weight	162.18 g/mol
Synonyms	1-(4,4-Difluorocyclohexyl)ethanone; 4,4-Difluorocyclohexyl methyl ketone; 4,4-Difluoro-1-acetylcyclohexane; 1-Acetyl-4,4-difluorocyclohexane; 4,4-Difluorocyclohexylmethylketone; 4,4-Difluoro-cyclohexyl methyl ketone; 4,4-Difluoro-1-cyclohexyl ethanone; 4,4-Difluorocyclohexan-1-yl methyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(4,4-Difluorocyclohexyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.