Description

2-Isopropoxy-5-Trifluoromethyl-Phenylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific trifluoromethyl and isopropoxy functional groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides and pesticides, leveraging the bioactivity of the trifluoromethyl group.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new chemical entities and reaction pathways in organic synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up production of specific APIs where the aniline hydrochloride moiety is required.
• Material Science: Potential application as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced materials.

Basic Information

Product Name	2-Isopropoxy-5-Trifluoromethyl-Phenylamine Hydrochloride
CAS No.	121307-23-1
Molecular Formula	C10H13F3NO•HCl
Molecular Weight	255.67 g/mol
Synonyms	2-Isopropoxy-5-(trifluoromethyl)aniline hydrochloride; 5-Trifluoromethyl-2-isopropoxyaniline hydrochloride; 1-Isopropoxy-4-amino-2-(trifluoromethyl)benzene hydrochloride; 2-Amino-4-isopropoxy-α,α,α-trifluorotoluene hydrochloride; Benzenamine, 2-isopropoxy-5-(trifluoromethyl)-, hydrochloride; 2-Isopropoxy-α,α,α-trifluoro-p-toluidine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Isopropoxy-5-Trifluoromethyl-Phenylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.