Description

(S)-3-Hydroxy-5-Methoxy-6-Methyl-2H-Pyran-4(3H)-One is a high-purity chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined hydroxyl and ketone functional groups, which are crucial for constructing complex molecular architectures with precise spatial orientation. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), natural product analogs, and specialized flavor or fragrance components.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including potential antibiotics, antivirals, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific chirality can enhance efficacy and reduce environmental impact.
• Fine Chemical Production: Serves as a building block for complex natural product analogs, specialty polymers, and high-value chemical entities.
• Flavor & Fragrance Industry: Potential precursor in the synthesis of stereochemically pure aroma chemicals and flavor compounds.
• Academic & Industrial R&D: A valuable reagent for methodological development in asymmetric synthesis and catalysis studies.
• Material Science: Can be utilized in the development of chiral ligands for catalysts or as a monomer for specialized polymeric materials.

Basic Information

Product Name	(S)-3-Hydroxy-5-Methoxy-6-Methyl-2H-Pyran-4(3H)-One
CAS No.	121043-40-1
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	(S)-5-Methoxy-6-methyl-4H-pyran-4-one-3-ol; (3S)-3-Hydroxy-5-methoxy-6-methyl-2H-pyran-4(3H)-one; (S)-3-Hydroxy-5-methoxy-6-methyl-4H-pyran-4-one; (S)-Dehydroacetic acid derivative; (S)-DHA lactone analog; (S)-3-Hydroxy-5-methoxy-6-methyl-4-pyrone; (S)-3-Hydroxy-5-methoxy-6-methyl-2H-pyran-4-one
EINECS	Contact for details

Quality Control

Our (S)-3-Hydroxy-5-Methoxy-6-Methyl-2H-Pyran-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and production standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.