Description

Propan-2-Yl 2-Chloro-5-[3-Methyl-2,6-Dioxo-4-(Trifluoromethyl)Pyrimidin-1-Yl]Benzoate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic benzoate structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in developing new small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in oncology and antiviral therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and fungicides, leveraging the trifluoromethylpyrimidine moiety.
• Chemical Research: Used in academic and industrial R&D for studying structure-activity relationships (SAR) and developing novel heterocyclic compounds.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of target molecules.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Propan-2-Yl 2-Chloro-5-[3-Methyl-2,6-Dioxo-4-(Trifluoromethyl)Pyrimidin-1-Yl]Benzoate
CAS No.	120890-70-2
Molecular Formula	C16H12ClF3N2O4
Molecular Weight	388.73 g/mol
Synonyms	Isopropyl 2-Chloro-5-(3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1(2H)-yl)benzoate; 1-Isopropyl 2-Chloro-5-(3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl)benzoate; 2-Chloro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]benzoic Acid Isopropyl Ester; Propan-2-yl 2-chloro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]benzoate; CAS 120890-70-2
EINECS	Contact for details

Quality Control

Our Propan-2-Yl 2-Chloro-5-[3-Methyl-2,6-Dioxo-4-(Trifluoromethyl)Pyrimidin-1-Yl]Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity by HPLC, residual solvents, and related substances are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.