Description

7-Chloro-6-Fluoro-1-Ethyl-1,4-Dihydro-4-Oxopyrido(2,3-C)Pyridazine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of potent antibacterial agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of next-generation quinolone and pyridazine-based therapeutics.

Application

• Key Intermediate for Antibacterial API Synthesis: Serves as a crucial building block in the production of new-generation fluoroquinolone antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of novel antibacterial compounds.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling up production for clinical trial material and commercial API manufacturing.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical development.

Basic Information

Product Name	7-Chloro-6-Fluoro-1-Ethyl-1,4-Dihydro-4-Oxopyrido(2,3-C)Pyridazine-3-Carboxylic Acid
CAS No.	120876-49-5
Molecular Formula	C₁₀H₇ClFN₃O₃
Molecular Weight	271.63 g/mol
Synonyms	7-Chloro-6-fluoro-1-ethyl-4-oxo-1,4-dihydropyrido[2,3-c]pyridazine-3-carboxylic acid; 1-Ethyl-7-chloro-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid; PD 117596; ABT-719 intermediate; Avarofloxacin intermediate; 120876-49-5; 7-Chloro-6-fluoro-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Chloro-6-Fluoro-1-Ethyl-1,4-Dihydro-4-Oxopyrido(2,3-C)Pyridazine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.