Description

6-Amino-4,4,5,7,8-Pentamethyldihydrocoumarin is a specialized amino-substituted dihydrocoumarin derivative with a unique pentamethylated structure. This compound serves as a valuable synthetic intermediate and building block in advanced organic synthesis, prized for its functionalized coumarin core. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or requiring a functionalized coumarin scaffold.
• Agrochemical Research: Used in the development of new pesticides, herbicides, or plant growth regulators where the amino-coumarin structure can impart specific biological activity.
• Organic Synthesis & Material Science: Serves as a precursor for creating complex heterocyclic compounds, dyes, or photoactive materials.
• Biochemical Research: Potential use as a fluorescent probe or a tag due to the inherent properties of the coumarin moiety, useful in assay development and diagnostic research.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	6-Amino-4,4,5,7,8-Pentamethyldihydrocoumarin
CAS No.	120372-42-1
Molecular Formula	C₁₆H₂₃NO₂
Molecular Weight	261.36 g/mol
Synonyms	6-Amino-4,4,5,7,8-pentamethyl-3,4-dihydro-2H-chromen-2-one; 6-Amino-4,4,5,7,8-pentamethyl-3,4-dihydrocoumarin; 4,4,5,7,8-Pentamethyl-6-amino-3,4-dihydrocoumarin; 2H-1-Benzopyran-2-one, 6-amino-3,4-dihydro-4,4,5,7,8-pentamethyl-; 6-Amino-4,4,5,7,8-pentamethyl-2-chromanone
EINECS	Contact for details

Quality Control

Our 6-Amino-4,4,5,7,8-Pentamethyldihydrocoumarin is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC/GC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.