Description

(S)-1-Z-2-tert-Butyl-3-Methyl-4-Imidazolidinone is a high-purity, chiral imidazolidinone derivative that serves as a critical building block and chiral auxiliary in advanced organic synthesis. Its value lies in enabling the stereoselective construction of complex molecules, which is essential for developing pharmaceuticals and fine chemicals with high biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and catalysts.

Application

• As a chiral auxiliary in asymmetric synthesis for the production of enantiomerically pure pharmaceutical intermediates.
• As a key ligand or organocatalyst in enantioselective catalytic reactions, such as aldol or Diels-Alder reactions.
• In the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• For the synthesis of complex natural products and fine chemicals requiring high stereochemical control.
• In process chemistry for scaling up the production of chiral compounds under GMP conditions.
• As a reference standard for analytical method development and quality control in chiral separation techniques.

Basic Information

Product Name	(S)-1-Z-2-tert-Butyl-3-Methyl-4-Imidazolidinone
CAS No.	119906-49-9
Molecular Formula	C9H16N2O
Molecular Weight	168.24 g/mol
Synonyms	(S)-1-Benzyl-2-tert-butyl-3-methylimidazolidin-4-one; (S)-1-Benzyl-2-tert-butyl-3-methyl-4-imidazolidinone; (S)-1-Benzyl-2-(tert-butyl)-3-methylimidazolidin-4-one; (S)-1-Bn-2-t-Bu-3-Me-4-imidazolidinone; (S)-1-Benzyl-2-(1,1-dimethylethyl)-3-methyl-4-imidazolidinone; MacMillan Catalyst First Generation; (S)-MacMillan Catalyst; Organocatalyst
EINECS	Contact for details

Quality Control

Our (S)-1-Z-2-tert-Butyl-3-Methyl-4-Imidazolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with high-purity research and pharmaceutical grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee reproducible performance in sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.