Description

n-(1-Trifluoromethyl-Ethylidene)Benzylamine is a specialized fluorinated organic building block characterized by its unique imine and trifluoromethyl functionalities. This compound is valued for its role as a key intermediate in the synthesis of advanced pharmaceutical and agrochemical agents, where the introduction of fluorine atoms is critical for modulating biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological efficacy.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
• Advanced Material Research: Employed in the creation of fluorinated polymers and specialty chemicals with unique surface properties and chemical resistance.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological mechanisms and diagnostic applications.

Basic Information

Product Name	n-(1-Trifluoromethyl-Ethylidene)Benzylamine
CAS No.	119561-23-8
Molecular Formula	C10H10F3N
Molecular Weight	201.19 g/mol
Synonyms	N-[(E)-3,3,3-Trifluoro-1-methylprop-1-en-1-yl]benzylamine; N-Benzyl-1,1,1-trifluoro-2-methylpropan-2-imine; 1-Trifluoromethyl-1-ethylidene-benzylamine; (E)-N-Benzyl-3,3,3-trifluoro-2-methylprop-1-en-1-amine; α-(Trifluoromethyl)ethylidenebenzylamine; Benzyl(1-trifluoromethylethylidene)amine; N-(1-Trifluoromethylethylidene)benzylamine
EINECS	Contact for details

Quality Control

Our n-(1-Trifluoromethyl-Ethylidene)Benzylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.