Description

Ethyl (3-Trimethylsilyl)-4-Pentenoate is a specialized organosilicon compound that serves as a valuable building block in advanced organic synthesis. Its unique structure, featuring both a silyl-protecting group and an ester-linked pentenoate chain, makes it a versatile reagent for constructing complex molecules with high precision. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for their synthetic workflows.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing functionalized alkene or silyl-protected motifs.
• Agrochemical Synthesis: Used in the production of novel pesticides and herbicides, where its reactive alkene group enables further functionalization.
• Organosilicon Chemistry: Acts as a precursor for silicon-containing polymers, resins, and specialty materials requiring specific silyl ester functionalities.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions, such as Heck or Suzuki couplings, for carbon-carbon bond formation.
• Academic & Industrial R&D: A critical reagent for method development and exploring new synthetic pathways in organic and medicinal chemistry laboratories.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex ester-based aroma chemicals.

Basic Information

Product Name	Ethyl (3-Trimethylsilyl)-4-Pentenoate
CAS No.	119554-74-4
Molecular Formula	C10H20O2Si
Molecular Weight	200.35 g/mol
Synonyms	4-Pentenoic acid, 3-(trimethylsilyl)-, ethyl ester; Ethyl 3-(trimethylsilyl)-4-pentenoate; 3-(Trimethylsilyl)-4-pentenoic acid ethyl ester; Ethyl 3-trimethylsilylpent-4-enoate; (3-Trimethylsilyl-4-pentenoic acid) ethyl ester; TMS-Pentenoate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl (3-Trimethylsilyl)-4-Pentenoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.430 - 1.440
Density (g/mL at 20°C)	0.88 - 0.92

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.