Description

2H-1-Benzopyran-2-Methanol, α,α'-[Iminobis(Methylene)]Bis[6-Fluoro-3,4-Dihydro-, (αs,α'S,2R,2'R)- is a high-purity, stereochemically defined chiral compound belonging to the benzopyran class. This molecule matters as a sophisticated pharmaceutical intermediate or building block for the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by R&D and production teams in the pharmaceutical and fine chemical industries, particularly those developing fluorinated therapeutics.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel fluorinated drug candidates.
• Asymmetric Synthesis: Used in stereoselective reactions to construct complex molecular architectures with defined chirality.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Fluorine Chemistry: The 6-fluoro substitution makes it valuable for developing compounds with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Potential use in developing labeled compounds for biochemical and cellular studies.
• Advanced Material Synthesis: May be utilized in the preparation of specialty polymers or liquid crystals with specific optical properties.

Basic Information

Product Name	2H-1-Benzopyran-2-Methanol, α,α'-[Iminobis(Methylene)]Bis[6-Fluoro-3,4-Dihydro-, (αs,α'S,2R,2'R)-
CAS No.	119365-30-9
Molecular Formula	C21H22F2N2O4
Molecular Weight	404.41 g/mol
Synonyms	(2R,2'R)-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]; (2R,2'R)-α,α'-(Iminodimethylene)bis(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol); 6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol, α,α'-[imino-bis(methylene)]bis-, (αS,α'S,2R,2'R)-; Chiral Bis(benzopyran) Derivative; Fluorinated Chiral Diol Intermediate; CAS 119365-30-9
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your R&D and cGMP manufacturing needs. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are available upon request. Our quality systems are designed to meet the stringent requirements for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is likely hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.