Description

(3E)-4-(1,2-Dimethyl-6-([2-(Trimethylsilyl)Ethoxy]Methoxy)Cyclohexyl)- 3-Buten-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique silyl-protected functional group. This compound is critical for enabling complex synthetic routes in modern organic chemistry, offering precise reactivity and stability for multi-step transformations. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Reagent: Used in advanced organic reactions, including cross-coupling and cyclization processes, due to its protected hydroxyl functionality.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for commercial pharmaceutical production.
• Academic Research: Used in university and institutional laboratories for developing new synthetic methodologies and exploring novel chemical spaces.
• Fine Chemical Production: Acts as a precursor in the manufacture of other specialized fine chemicals and custom synthesis projects.

Basic Information

Item	Detail
Product Name	(3E)-4-(1,2-Dimethyl-6-([2-(Trimethylsilyl)Ethoxy]Methoxy)Cyclohexyl)- 3-Buten-2-One
CAS No.	119018-20-1
Molecular Formula	C18H34O3Si
Molecular Weight	326.55 g/mol
Synonyms	(3E)-4-[1,2-Dimethyl-6-({2-[(trimethylsilyl)oxy]ethoxy}methoxy)cyclohexyl]but-3-en-2-one; 4-(1,2-Dimethyl-6-{[2-(trimethylsilyl)ethoxy]methoxy}cyclohexyl)-3-buten-2-one; (E)-4-(1,2-Dimethyl-6-((2-(trimethylsilyl)ethoxy)methoxy)cyclohexyl)but-3-en-2-one; SEM-protected cyclohexyl butenone derivative; 119018-20-1; But-3-en-2-one, 4-[1,2-dimethyl-6-[[2-(trimethylsilyl)ethoxy]methoxy]cyclohexyl]-, (3E)-
EINECS	Contact for details

Quality Control

Our (3E)-4-(1,2-Dimethyl-6-([2-(Trimethylsilyl)Ethoxy]Methoxy)Cyclohexyl)- 3-Buten-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.