Description

6,8-Dichloro-2H-chromene-3-carboxylic acid methyl ester is a high-purity, synthetically valuable chromene derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Research: Building block for developing new-generation herbicides, fungicides, and plant growth regulators with enhanced activity.
• Organic Synthesis: Versatile synthon for constructing fused heterocyclic systems and complex natural product analogs in academic and industrial research.
• Material Science: Potential monomer or precursor for developing specialty polymers and functional organic materials with specific optical or electronic properties.
• Chemical Biology: Used as a probe or scaffold in the development of enzyme inhibitors and molecular tools for biological studies.

Basic Information

Product Name	6,8-Dichloro-2H-chromene-3-carboxylic acid methyl ester
CAS No.	118693-22-4
Molecular Formula	C11H8Cl2O3
Molecular Weight	259.09 g/mol
Synonyms	Methyl 6,8-dichloro-2H-chromene-3-carboxylate; 6,8-Dichloro-2H-1-benzopyran-3-carboxylic acid methyl ester; 6,8-Dichlorochromene-3-carboxylic acid methyl ester; 2H-Chromene-3-carboxylic acid, 6,8-dichloro-, methyl ester; Methyl 6,8-dichloro-2H-1-benzopyran-3-carboxylate; 118693-22-4
EINECS	Contact for details

Quality Control

Our 6,8-Dichloro-2H-chromene-3-carboxylic acid methyl ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.