Description

(R)-Glycidyl-4-Nitrobenzenesulfonate is a high-purity chiral building block and electrophilic reagent. This compound is valued for its role in the stereoselective synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing chiral centers and introducing functional groups with high enantiomeric fidelity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially β-blockers and other cardiovascular drugs.
• Asymmetric Synthesis: Used as an electrophilic glycidylating agent in reactions to introduce chiral epoxide functionalities into target molecules.
• Agrochemical Research: Serves as a building block for developing chiral herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.
• Material Science Precursor: Used in the research of advanced polymers and resins where chiral epoxide monomers are required.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic and medicinal chemistry focused on stereochemistry.

Basic Information

Product Name	(R)-Glycidyl-4-Nitrobenzenesulfonate
CAS No.	118629-64-4
Molecular Formula	C9H9NO6S
Molecular Weight	259.24 g/mol
Synonyms	(R)-Glycidyl 4-nitrobenzenesulfonate; (R)-(-)-Glycidyl 4-nitrobenzenesulfonate; (R)-(-)-Glycidyl tosylate analog; (R)-Oxiran-2-ylmethyl 4-nitrobenzenesulfonate; (2R)-(-)-Glycidyl 4-nitrobenzenesulfonate; (R)-Epoxypropyl 4-nitrobenzenesulfonate; p-Nitrobenzenesulfonic acid (R)-glycidyl ester; (R)-GNS
EINECS	Contact for details

Quality Control

Our (R)-Glycidyl-4-Nitrobenzenesulfonate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.