Description

1H-Isoindole-1-Carboxylicacid,2,3-Dihydro-,(S)-(9Ci) is a chiral, non-racemic organic compound belonging to the isoindoline class, serving as a valuable synthetic building block. This compound matters for its role as a key chiral intermediate in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). Industries that need it include pharmaceutical R&D, fine chemical manufacturing, and academic research laboratories focused on asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Asymmetric Catalysis Research: Used as a precursor or ligand framework in the development of new chiral catalysts for enantioselective transformations.
• Fine Chemical Synthesis: Employed in the preparation of complex, high-value specialty chemicals requiring specific stereochemistry.
• Agrochemical Development: Serves as a building block for creating chiral active ingredients with enhanced biological activity and selectivity.
• Academic & Contract Research: Utilized in university and CRO settings for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	1H-Isoindole-1-Carboxylicacid,2,3-Dihydro-,(S)-(9Ci)
CAS No.	118312-39-3
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	(S)-2,3-Dihydro-1H-isoindole-1-carboxylic acid; (S)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid (related structural analog); (S)-Isoindoline-1-carboxylic acid; L-Isoindoline-1-carboxylic acid; (S)-1-Carboxyisoindoline; 1H-Isoindole-1-carboxylic acid, 2,3-dihydro-, (S)-; (9CI); 118312-39-3; (S)-Tetrahydroisoquinoline-1-carboxylic acid (common misnomer)
EINECS	Contact for details

Quality Control

Our 1H-Isoindole-1-Carboxylicacid,2,3-Dihydro-,(S)-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is compatible with strong acids and organic solvents but should be stored separately from incompatible materials. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.