Description

4H-1-Benzopyran-4-One, 2,3-Dihydro-3,5,7-Trihydroxy-3-[(4-Methoxyphenyl)Methyl]-, (R)- is a high-purity, optically active flavonoid derivative of significant interest in advanced research and development. This compound matters for its role as a key chiral intermediate and reference standard in the synthesis of complex bioactive molecules. It is primarily needed by pharmaceutical R&D teams, nutraceutical formulators, and academic researchers focused on developing novel therapeutics, particularly in areas like metabolic and neurological health.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel drug candidates targeting specific biological pathways.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality control of related flavonoid compounds.
• Nutraceutical & Cosmetic R&D: Investigated for incorporation into advanced formulations for its potential bioactive properties, requiring high-purity, well-characterized ingredients.
• Biochemical Research: Employed in enzymatic and receptor-binding studies to understand structure-activity relationships (SAR) of flavonoid derivatives.
• Asymmetric Synthesis: Utilized in chiral synthesis protocols to study and develop new stereoselective reactions.

Basic Information

Product Name	4H-1-Benzopyran-4-One, 2,3-Dihydro-3,5,7-Trihydroxy-3-[(4-Methoxyphenyl)Methyl]-, (R)-
CAS No.	118204-64-1
Molecular Formula	C17H16O6
Molecular Weight	316.31 g/mol
Synonyms	(R)-3,5,7-Trihydroxy-2-(4-methoxybenzyl)chroman-4-one; (R)-Hesperetin 4'-Methyl Ether; (R)-5,7-Dihydroxy-2-(4-methoxybenzyl)-4-chromanone; (R)-Homopterocarpin; (R)-3,5,7-Trihydroxy-3-[(4-methoxyphenyl)methyl]-2,3-dihydro-4H-chromen-4-one; (R)-Flavanone Derivative; (R)-Methoxybenzyl Dihydroflavonol
EINECS	Contact for details

Quality Control

Our production of this chiral compound adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC for chiral purity and assay, NMR for structural confirmation, and specific tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC, Area %)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (R)-enantiomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.