Description

1-Amino-4-Phenylbutan-2-Ol CAS NO 117974-11-5 is a chiral amino alcohol derivative featuring both phenyl and amino functional groups on a butanol backbone. This compound matters as a versatile and valuable chiral building block in asymmetric synthesis, enabling the creation of complex molecules with high stereochemical purity. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of β-blockers, antidepressants, and other bioactive molecules requiring specific stereochemistry.
• Asymmetric Catalyst Ligand: Used to prepare chiral ligands for metal-catalyzed reactions, such as asymmetric hydrogenations and C-C bond formations.
• Agrochemical Synthesis: Serves as a precursor in the manufacturing of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Employed in research and production of complex natural products, flavors, and fragrances.
• Material Science Research: Investigated for the development of chiral polymers, liquid crystals, and advanced functional materials.

Basic Information

Product Name	1-Amino-4-Phenylbutan-2-Ol
CAS No.	117974-11-5
Molecular Formula	C10H15NO
Molecular Weight	165.23 g/mol
Synonyms	4-Phenyl-2-aminobutan-1-ol; 2-Amino-4-phenyl-1-butanol; 4-Phenyl-2-amino-1-butanol; (RS)-1-Amino-4-phenylbutan-2-ol; (±)-1-Amino-4-phenyl-2-butanol; 4-Phenyl-1,2-butanediamine (misnomer, verify context); 2-Hydroxy-4-phenylbutylamine; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 1-Amino-4-Phenylbutan-2-Ol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess (where applicable), and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.