Description

1-(Trifluoromethanesulfonyl)-1H-Benzotriazole is a specialized trifluoromethanesulfonyl (triflyl) transfer reagent and a key intermediate in organic synthesis. This compound matters for its ability to efficiently introduce the highly electron-withdrawing triflyl group, enabling critical transformations in the synthesis of complex molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries, as well as by manufacturers of advanced materials and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sulfonamide or triflyl-protected functional groups.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethanesulfonyl moiety enhances biological activity and stability.
• Peptide Chemistry: Serves as a coupling agent or activating reagent for the formation of peptide bonds under mild conditions.
• Polymer Science: Employed in the production of specialty polymers and materials, including those with specific sulfonyl-based functionalities.
• Catalyst and Ligand Preparation: Utilized in the synthesis of novel metal-organic catalysts and ligands for asymmetric synthesis.
• Chemical Research: A versatile reagent in academic and industrial R&D labs for nucleophilic substitution reactions and the preparation of sulfonate esters.

Basic Information

Product Name	1-(Trifluoromethanesulfonyl)-1H-Benzotriazole
CAS No.	117632-84-5
Molecular Formula	C7H4F3N3O2S
Molecular Weight	251.18 g/mol
Synonyms	1H-Benzotriazole, 1-[(trifluoromethyl)sulfonyl]-; 1-Trifluoromethanesulfonylbenzotriazole; Benzotriazol-1-yl trifluoromethanesulfonate; Triflyl Benzotriazole; Tf-Bt; 1-(Triflyl)benzotriazole; N-Triflylbenzotriazole; 1-(Trifluoromethanesulfonyl)benzotriazole
EINECS	Contact for details

Quality Control

Our 1-(Trifluoromethanesulfonyl)-1H-Benzotriazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.