Description

(3S)-3,4-Dihydro-5-Methoxy-2H-1-Benzopyran-3-Amine CAS NO 117422-50-1 is a chiral, non-racemic benzopyran derivative featuring an amine functional group. This compound is a valuable chiral building block and intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical sector. It is primarily sought after by research institutions and manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Utilized as a chiral amine precursor or auxiliary in stereoselective chemical reactions to construct enantiomerically pure compounds.
• Medicinal Chemistry Research: Serves as a core scaffold or a starting material for generating compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials where specific stereochemistry is required.
• Academic & Industrial R&D: Used in methodological development and catalysis research focused on new synthetic pathways involving benzopyran motifs.

Basic Information

Product Name	(3S)-3,4-Dihydro-5-Methoxy-2H-1-Benzopyran-3-Amine
CAS No.	117422-50-1
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(3S)-3-Amino-3,4-dihydro-5-methoxy-2H-1-benzopyran; (S)-3-Amino-5-methoxychroman; 5-Methoxy-3,4-dihydro-2H-1-benzopyran-3-amine, (3S)-; (S)-5-Methoxychroman-3-amine; (3S)-5-Methoxy-3,4-dihydro-2H-chromen-3-amine; (S)-3-Amino-5-methoxy-3,4-dihydro-2H-chromene; (3S)-3-Amino-5-methoxy-3,4-dihydro-2H-chromene
EINECS	Contact for details

Quality Control

Our (3S)-3,4-Dihydro-5-Methoxy-2H-1-Benzopyran-3-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.